• Santacruzamate A AAT enzyme activity was readily detected in

  2024-06-24

  

  AAT enzyme activity was readily detected in crude cell-free extracts obtained from berry tissues of all accessions but displayed different substrate selectivities (Fig. 2). Cell-free extracts derived from ‘Muscat Hamburg’ berries showed the highest AAT activity with all alcoholic substrates tested,

• uncouplers of oxidative phosphorylation br Discussion In a s

  2024-06-24

  

  Discussion In a series of linear mixed effects models of longitudinal neuroanatomical change, we have identified genetic risk variants associated with an increase in uncouplers of oxidative phosphorylation shape asymmetry in AD. The closest genes associated with significant SNPs include BIN1 (rs

• The cavity volume of the binding pocket may differ not

  2024-06-24

  

  The cavity volume of the binding pocket may differ not only between species but also among various AhR/ARNT isoforms within a single species. It is noteworthy that even a single amino Epiandrosterone substitution within a binding pocket may result in a change in the cavity volume. This, in turn, ma

• In this study in an

  2024-06-24

  

  In this study, in an effort to explore the possible role of 5-HT6 receptors in mediating the memory-enhancing effects of YL-0919, we first assessed the memory-enhancing effects of YL-0919 in the Morris water maze, object recognition test and step-down passive avoidance task. In addition, we then inv

• Some alterations in the integrity of cell

  2024-06-24

  

  Some alterations in the integrity of cell membranes caused by toxic agents can be determined by measuring certain enzymes released by damaged cells [8]. The cholinesterases, for example, catalyze the hydrolysis of Amoxapine (ACh) in choline and acetic acid. Theses enzymes are divided into two types

• Our results using RT PCR confirm earlier findings Wilisch

  2024-06-24

  

  Our results using RT-PCR confirm earlier findings (Wilisch et al., 1999, Bruno et al., 2004) including the presence of both the P3A+ and P3A− isoforms of the α-subunit (Beeson et al., 1990). The lack of detection of the ε-subunit mRNAs in some thymomas, and lack of α-, β-, δ- and γ-subunit mRNAs by

• Compounds were profiled for their

  2024-06-24

  

  Compounds – were profiled for their inhibitory activity against dipeptidyl peptidase-IV Activity and/or Structure Homologues (DASH) [e.g. DPP2, DPP8 and DPP9] and non-DASH [eg. post-proline cleaving enzyme (PPCE), neutral endopeptidase (NEP), aminopeptidase P (APP), aminopeptidase N (APN)] enzymes.

• Additionally regulation of GPCR heteromerization by specific

  2024-06-24

  

  Additionally, regulation of GPCR heteromerization by specific ligands may depend not only on the affinity of ligands for receptors, but also on presence of different interacting proteins co-localizing with the receptors in the specific cell, which may induce some conformational changes and contribut

• Because activation of HT A receptor is capable of

  2024-06-24

  

  Because activation of 5-HT2A receptor is capable of facilitating dopamine cell activity and dopamine release (Bortolozzi et al., 2003), and this action of dopamine is known to mediate rat maternal behavior, especially maternal motivation (Afonso et al., 2007, Febo et al., 2010, Li and Fleming, 2003,

• br Materials and methods br

  2024-06-22

  

  Materials and methods Results Discussion Proteomics analyses generate mountains of data, expression information for hundreds or thousands of proteins in a single experiment (Wojcik and Schächter, 2000). Recently proteomics and bioinformatics provide new understandings about the processes in

• In this study we observed the ATPase

  2024-06-22

  

  In this study, we observed the ATPase activity of RaGroEL at various temperatures and metal ions conditions and the role of GroES in the ATPase activity of RaGroEL. Furthermore, we quantified the expression of groEL genes under different abiotic stresses, including temperature, pH, salt and oxygen s

• Production of reactive oxygen species ROS during

  2024-06-22

  

  Production of reactive oxygen species (ROS) during RSV infection is one the important ways that neutrophils can injure the lungs [2], [24], [25]. Lipoxygenases are considered as an important source of producing ROS inside the Pyoluteorin [26]. Several studies have indicated that the 12/15-LOX is a

• br Introduction In the past two

  2024-06-22

  

  Introduction In the past two decades, graphene and graphene based nanomaterials with unique physicochemical properties have attracted great attentions in many fields including biomedicine and biotechnology. Graphene oxide (GO) and its derivatives have shown promising potential as biological and c

• According to the diversity in molecular skeletons aromatase

  2024-06-22

  

  According to the pramipexole dihydrochloride in molecular skeletons, aromatase inhibitors can be categorized into two types: steroidal and non-steroidal blockers [6]. Steroidal AI (e.g., exemestane in Fig. 1) derived from the substrate androstenedione interacts with aromatase through chemical actio

• The isoelectric point of CL

  2024-06-22

  

  The isoelectric point of CL-ARG was determined by native IEF at a 98 receptor gradient in the range (3–10) using standard protein markers with known isoelectric points. Native IEF reveals the presence of only one major band for CL-ARG with a slightly neutral-basic pI value of about 7.7. The calcula

14787 records 97/986 page Previous Next First page 上5页 96979899100 下5页 Last page