• Michel et al calculated the mutual solubilities

  2019-11-30

  

  Michel et al. [34] calculated the mutual solubilities of water and hydrocarbons by a cubic equation of state. They asserted that conventional mixing rules can not satisfactorily describe the hydrogen bonding compounds. Kabadi and Danner [35] applied a modified form of Soave-Redlich-Kwong equation of

• Introduction Klebsiella pneumoniae a Gram negative enteric b

  2019-11-30

  

  Introduction Klebsiella pneumoniae, a Gram-negative enteric bacterium, is an organism with significance in both biomedicine and biotechnology. Some of the strains of K. pneumoniae are opportunistic pathogens, which can cause suppurative infection, pneumoniae and urinary tract infection in humans (B

• acpt synthesis It seems plausible that this ESC

  2019-11-30

  

  It seems plausible that this ESC-driven effect relies on a paracrine signaling. Numerous studies showed that the Fgf4 (fibroblast growth factor 4)/MAPK (mitogen-activated protein kinase) pathway is involved in PE differentiation in mouse acpt synthesis (Chazaud et al., 2006), (Frankenberg et al., 2

• The pathogenesis of formation of an intradural tumor

  2019-11-30

  

  The pathogenesis of formation of an intradural tumor is unclear. Initially, several lines of evidence suggested a neural crest cell of origin for Ewings’s sarcoma based on expression of neuroectodermal markers on tumor nvp-aew541 [45,46]. However more recently, studies have shown that expression of

• Docking experiments showed that Me MeGlcA Xyl and MeGlc

  2019-11-30

  

  Docking experiments showed that Me-MeGlcA3Xyl4 and MeGlc3Xyl4 were bound to EcXyn30A and the R293A variant in the same way as MeGlcA3Xyl4, having MeGlcA or its modified forms accommodated in the -2b subsite. All ligands were coordinated by the same KN-93 and no new interactions were observed. The o

• br Introduction Epithelial mesenchymal transition EMT is a b

  2019-11-30

  

  Introduction Epithelial-mesenchymal transition (EMT) is a biological process by which epithelial resveratrol lose cell polarity and cell-cell adhesion, and gain mesenchymal features with an increase of migratory and invasive properties [1]. EMT is essential for mesoderm formation during embryo de

• br Conflicts of interest br Financial support NZ is

  2019-11-30

  

  Conflicts of interest Financial support NZ is an Established Investigator of the Dutch Heart Foundation (2013T111) and is supported by an ERC Consolidator grant (617376) from the European Research Council and by a Vici grant from the Netherlands Organization for Scientific Research (NWO; 91818

• Psalmotoxin 1 The potential impact of multiple washings

  2019-11-30

  

  The potential impact of multiple washings on DNA retention in semen stains had not previously been addressed. In the present study, multiple washes of semen-stained cotton cloth produced only a minimal loss of recovered DNA suggesting that multiple washes may not materially affect DNA recovery (Fig.

• Estrogen treatment in postmenopausal women requires

  2019-11-29

  

  Estrogen treatment in postmenopausal women requires combination with a progestogen in order to prevent endometrial stimulation. This is not necessary, however, with tibolone as progestogenic activity is associated with its Δ4-metabolite that is formed in the liver, as well as locally in the endometr

• substance p Given the molecular pharmacology and in vitro me

  2019-11-29

  

  Given the molecular pharmacology and in vitro metabolism data, we proceeded to evaluate the in vivo pharmacokinetics of . Mice (=3) were subsequently administered a subcutaneous dose (5mg/kg) with intermittent plasma collections to measure systemic levels of (). Compound achieved a maximum plasma

• In accordance with its original discovery EBI

  2019-11-29

  

  In accordance with its original discovery, EBI2 may play its major role in response to viral infections or in a pathological context such as in autoimmunity. Although we found a significant delay of onset in the Th17 transfer EAE model, active EAE was unchanged in absence of EBI2. At the moment, we

• The best characterized APC C substrates

  2019-11-29

  

  The best-characterized APC/C substrates are recruited via various linear motifs (e.g., D boxes, KEN boxes, and ABBA motifs) that serve as degrons, binding to distinct regions of the β-propeller domain of a coactivator (Figure 1, Figure 3B) (reviewed in [44]). In addition, D boxes also simultaneously

• Organometallic compounds exhibited remarkable potential for

  2019-11-29

  

  Organometallic compounds exhibited remarkable potential for the development of new cancer drugs not only due to the direct cytotoxicity but also to the drug targeting and active anticancer immune response ability [4]. Among the organometallic compounds, ferrocene is one of the most well-known compou

• We have compared the potency of a

  2019-11-29

  

  We have compared the potency of a series of DNA-directed alkylating agents, including N-mustard-acridine, N-mustard-quinoline, and N-mustard-quinazoline conjugates previously synthesized in our laboratory [7], [13], and currently used drugs (oxaliplatin, cisplatin, or 5-FU) for the treatment of CRC

• Methylated CpGs can recruit transcriptional co

  2019-11-29

  

  Methylated CpGs can recruit transcriptional co-repressors to prevent transcription factors (TFs) from promoting gene expression by tightly packing gallamine structures [38]. Two CpG islands in the IPT5b promoter region showed higher methylation level in M9 rootstock compared to Mr (Fig. 3b). Howeve

15226 records 937/1016 page Previous Next First page 上5页 936937938939940 下5页 Last page