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ascorbic acid australia Based on the tonic phasic theory var
2020-07-27
Based on the tonic-phasic theory, variations in levels of DA via COMT may be beneficial or detrimental for performance depending on the cognitive demands of the task at hand (Bilder, Volavka, Lachman, & Grace, 2004). The Met allele, associated with high tonic DA transmission and cortical D1 stimulat
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The detection of galactomannan GM a
2020-07-25
The detection of galactomannan (GM), a polysaccharide that is released during Aspergillus growth, is a useful and reliable non-invasive diagnostic test for screening and management of aspergillosis and is often more sensitive than culture (Schelenz et al., 2015, Fisher et al., 2013). The level of ga
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Since PTKs are involved in numerous
2020-07-25
Since PTKs are involved in numerous aspects of cell function, their regulation is critical for cell survival and function. The carboxyl-terminal tyrosine of Src-family PTKs is a key site of regulation. Phosphorylation on this carboxyl-terminal tyrosine contributes to the induction of a conformationa
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ci-1033 receptor Progesterone s metabolite THP may also be m
2020-07-25
Progesterone\'s metabolite, 3α,5α-THP, may also be mediating burying and freezing responses. Results show female Long–Evans rats in behavioral estrous have higher P4 levels in serum, ci-1033 receptor and hippocampus compared to diestrous female Long–Evans rats. Additionally, ovx female Long–Evans r
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br Cytochrome P monooxygenases Cytochrome P monooxygenases P
2020-07-25
Cytochrome P450 monooxygenases Cytochrome P450 monooxygenases (P450s) belong to one of Nature’s most versatile group of enzymes for C–H functionalization and are able to perform challenging regioselective and stereoselective activations of remote, unactivated C(sp3)–H bonds, for which there are o
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In the present study we
2020-07-25
In the present study, we investigated the deeper role of eNOS in the pathogenesis of nasal polyps and analyzed the influence of 1,8-cineol on nasal polyp gene and protein expression of eNOS in vitro. Different studies dealt with the localization and expression of eNOS in nasal polyps and nasal mucos
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br Clinical potential of ET receptor biased ligands Is
2020-07-25
Clinical potential of ET receptor biased ligands Is there a clinical need for ET receptor biased ligands? Evidence is strongest from research in epithelial ovarian cancer demonstrating that ET-1 stimulated ETA-mediated β-arrestin signalling leads to activation of the oncogenic mediator NF-κB [21]
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Nilvadipine As the first allotetraploid fish in the
2020-07-25
As the first allotetraploid fish in the world, our lab selectively breed the allotetraploid hybrid fish (4nAT, 4n = 200) from the distant hybridization offspring F3 of female Red Crucian Carp (Carassius auratus red var., abbreviated as RCC, 2n = 100) and male Common Carp (Cyprinius carpio L., abbrev
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Support for Cloninger s personality theory comes
2020-07-25
Support for Cloninger\'s personality theory comes also from molecular genetic studies. Given the high heritability of personality it is plausible that gene variants explain variance in RD. In 8602 to endocrine studies, which relate hormone levels mostly in the periphery (blood, saliva, urine) to pe
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TgTCEA from petals TgTCEA and TgTCEB from pollen grains
2020-07-25
TgTCEA from petals (TgTCEA1) and TgTCEB from pollen grains (TgTCEB1) were used throughout the study. The recombinant enzymes were expressed in , and purified as the His-tag-free forms as described previously., Enzyme reactions were performed at 4 mM substrates under the same conditions as described
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We experienced difficulties in observing
2020-07-24
We experienced difficulties in observing maturation of hESC retinas in rd1 mice even with immunosuppression, but with NOG-rd1-2J mice the transplanted hESC retinas consistently developed mature ONL with rod and cone opsins. Furthermore, graft photoreceptors show signs of developing IS/OS structures
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Our previous studies have shown that
2020-07-24
Our previous studies have shown that in a preimplantation mouse embryo the proportion of inner to outer cells (i.e. precursors of ICM and TE, respectively) is regulated by a different frequency of differentiative cell divisions at the 8- and 16-cell stages. Low number of inner blastomeres generated
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In SLO permeabilized human sperm the
2020-07-24
In SLO-permeabilized human sperm, the AR elicited by calcium, persistently active Arf6 [41] and Rab3A, 8-pCPT-2′-O-Me-cAMP [8], diacylglycerol and a non-hydrolyzable analog [35], is sensitive to the PLC blocker U73122. Furthermore, 8-pCPT-2′-O-Me-cAMP elicits a calcium signal in non-permeabilized sp
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br A major physiological action of ET is to function
2020-07-24
A major physiological action of ET-1 is to function as one of the most powerful vasoconstrictors of human blood vessels. As such, ET-1 plays a major role in regulating vascular function in all organ systems, including the kidney (Fig. 1). As in other vessels, ET-1 is thought to be released from en
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The redox sensitive transcription factor NF B is reported to
2020-07-24
The redox sensitive transcription factor NF-κB is reported to play a crucial role in the COPD pathogenesis via up regulating the expression of several cytokines, chemokines, growth factors, and adhesion molecules [71]. Incidentally, we and others have shown that PARP-1 modulates the NF-κB activation
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