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Carbonization and decarbonation are two different phases in
2021-04-09

Carbonization and decarbonation are two different phases in the decomposition of rice husk. Silica in RHA melts around 1440°C [5]. Burning of rice husk at temperature lower than 800°C produces reactive amorphous silica which contains approximately 90% silica, whereas above this temperature some crys
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Upon assembly of HLA tetramers loaded
2021-04-09

Upon assembly of HLA tetramers loaded with either of the two peptide versions, we could query the T cell repertoires of RA subjects and healthy individuals for the presence of cognate T Cy3 NHS ester (non-sulfonated) recognizing the respective peptide-HLA complexes. We found no significant differen
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Pyrene azide 3 Gupta et al have shown that
2021-04-09

Gupta et al have shown that a genetic variant associated with the 5 vascular diseases (coronary artery disease, migraine, carotid artery dissection, fibro-muscular dysplasia, and hypertension) is a distal regulator of the ET-1 gene [30]. They found that a single nucleotide polymorphism (SNP) located
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br Conflicts of interest br Introduction Arylamine N
2021-04-09

Conflicts of interest Introduction Arylamine N-acetyltransferase 1 (NAT1, EC 2.3.1.5) is a cytosolic enzyme that catalyses the acetylation of small molecule arylamines, hydrazines and sulphonamides (Hein, 2002). Found in most Medroxyprogesterone sale in the body, NAT1 expression is regulated
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With the narrow SAR of the
2021-04-08

With the narrow SAR of the tail favouring the ortho sulfone group, we examined the remaining position open to substitution at the pyrazole 3-position, in an attempt to at least moderate the excessive human PPB (). Lipophilic groups in this position maintained huge shifts in potency in the absence or
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It is generally thought that the
2021-04-08

It is generally thought that the nature of a memorial and the meaning attributed to it protease activated receptor by a tourist determines, at least in part, the behaviour that is socially appropriate (Mayo, 1988). Duncan (1995) argues however, that certain places are structured in such a way that t
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neurokinin 1 receptor The effect of the simple dopaminergic
2021-04-08

The effect of the simple dopaminergic tonic/phasic model on cognitive processing has been investigated by a few studies (Nolan et al., 2004; Rosa et al., 2010). Rosa et al. (2010), using a Stroop task that requires different levels of cognitive flexibility and stability, observed an association betw
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br Introduction br Multiple levels
2021-04-08

Introduction Multiple levels of CK2/AKT cross-talk Isoform-specific signaling in CK2/AKT cross-talk Particularly relevant to the scope of this review, it has been shown that depletion of the CK2 catalytic α′ subunit is more effective than that of the α subunit at reducing AKT Ser129 phospho
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Herein we further established a
2021-04-08

Herein, we further established a dynamic DNA self-assembly activated hemin-mimetic enzymes system by embedding DNA-hemin into an entropy-driven DNA-assembly for fluorescent biosensing. The entropy-driven dynamic DNA-assembly is one of the toehold-mediated isothermal strand displacement reactions, wh
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TCS 3035 In a study carried out by Aunis
2021-04-07

In a study carried out by Aunis et al. the properties of soluble DBH and membrane bound were examined [23]. The membrane bound enzyme was shown in TCS 3035 to the soluble form to have thermal denaturation at higher temperatures of 43.5–44°C. Similar discontinuities in the Arrhenius plots were obta
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br Materials and methods br Results
2021-04-07

Materials and methods Results Discussion The present study shows that 1) overexpression of wild-type or mutant α-SYN interferes with forskolin-induced DBH up-regulation, 2) α-SYN enters into the nucleus and is able to bind to CRE region, compete for CREB, and attenuate CRE-mediated transcri
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The purposes of this study
2021-04-07

The purposes of this study is to develop an experimental model of CysLT2 receptor-mediated LTC4-induced lung air-trapping in guinea pigs using S-hexyl GSH, and to clarify the mechanism underlying response to such trapping using montelukast, a CysLT1 receptor antagonist, BayCysLT2RA, a CysLT2 recepto
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CXCL mediated cell migration is facilitated by the interacti
2021-04-07

CXCL16 mediated cell migration is facilitated by the interaction of soluble CXCL16 with CXCR6, expressed predominantly on the cell surface of CD4+ Th1 cells, cancer infiltrating lymphocytes and platelets (Borst et al., 2012, Kim et al., 2001, Liao et al., 1997, Wilbanks et al., 2001). CXCR6 is invol
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The synthesis of tricyclic analogs is
2021-04-07

The synthesis of tricyclic analogs 28–33 is described in Scheme 3. Oxidative C–C bond cleavage of the terminal olefin of 39i afforded a tricyclic product 52 without isolation of an aldehyde expected as an intermediate. Aminolysis of the chloride 52 with optionally substituted anilines afforded 28–30
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Another potential source of variable affinities is inherent
2021-04-07

Another potential source of variable affinities is inherent in the method of RBA determination. While several reports simply use relative IC50 values as RBAs [11], [12], [13], [14], [15], these are only an approximate measure of relative affinity since IC50 varies due to experimental and biological
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